Jump directly to the content
SURVIVING PAIN

Where is MTV VJ Karen Duffy now- from jet-setting host & George Clooney’s rumored girlfriend to rare disease survivor

KAREN Duffy is best known for being a VJ on MTV, but now being a survivor of a rare disease, fans are wondering where she is now.

From being George Clooney's rumored girlfriend to writing a book about her illness, Karen has captured the hearts of many.

TV Personality Karen Duffy attends the Best Friends Animal Sactuary Benefit on November 6, 1993 at Chateau Marmont Hotel in West Hollywood, California
10
TV Personality Karen Duffy attends the Best Friends Animal Sactuary Benefit on November 6, 1993 at Chateau Marmont Hotel in West Hollywood, CaliforniaCredit: Getty
Karen Duffy Lambros attends a screening of “The Tender Bar” at Museum of Modern Art on December 09, 2021 in New York City
10
Karen Duffy Lambros attends a screening of “The Tender Bar” at Museum of Modern Art on December 09, 2021 in New York CityCredit: Getty

Born in New York City on May 23, 1962, Karen is the daughter of Carol, a homemaker, and Phil Duffy, a developer.

She was raised catholic, but attended a public school in New Jersey.

Before enterting showbiz, Karen attended the University of Colorado Boulder, where she earned a degree in recreational therapy.

She didn't know that her life was about to dramatically change.

ENTERING SHOWBIZ

A few years after college, Karen started modeling and acting in TV commercials.

But her life, and fame, changed when she became the Video Jockey (VJ) for MTV in the early 1990s, under the name Duff.

Karen Duffy during 1992 MTV Video Music Awards in Los Angeles, California
10
Karen Duffy during 1992 MTV Video Music Awards in Los Angeles, CaliforniaCredit: Getty

During that time, the VJ had small roles in a number of films including Dumb and Dumber, Blank Check, Malcolm X, and more.

The actress has over 20 credits to her name, but has not starred in anything since 2009.

By 1995, she was working as correspondant for documentary filmmaker, Michael Moore for his shows, TV Nation and The Awful Truth.

Karen ventured into other aspects of her career in the '90s.

She became a "Charlie Girl" for Revlon and the face of Almay Cosmetics.

In 1994, Karen co-hosted the pay-per-view TV event, Elvis: The Tribute, with singer Kris Kristofferson.

NOT CLOON-EYING AROUND

Karen Duffy and George Clooney attend UNIVERSAL PICTURES and EDMISTON & CO. Host a Privatel Screening of LEATHERHEADS at The Museum of Modern Art on April 3, 2008 in New York City
10
Karen Duffy and George Clooney attend UNIVERSAL PICTURES and EDMISTON & CO. Host a Privatel Screening of LEATHERHEADS at The Museum of Modern Art on April 3, 2008 in New York CityCredit: Getty

While at the height of her fame, Karen was rumored to be dating George Clooney.

However, the two have just been lifelong friends and supported each other over the years.

The two were so close that they attended the 1995 Emmy Awards together.

Karen Duffy and George Clooney at the 1995 Emmy Awards
10
Karen Duffy and George Clooney at the 1995 Emmy AwardsCredit: ZUMAPRESS.com

That was the last day of her life that she wasn't in pain.

“I was with George the last night I was healthy and, literally, this illness hit me like a bus,"

"It was the next day that I became symptomatic with sarcoidosis. That photo marks the end of my healthy life with one of the most charming and hilarious gentlemen. Talk about going out with a bang!"

The day after the Emmy's, she woke up with an excruciating head and neck ache.

Flying from Los Angeles to New York City, her doctor found an inoperable "mostaccioli-sized lesion" against her brain stem and spinal cord.

It crushed her nerves, which caused unimaginable pain.

Nine months later, doctors diagnosed her with sarcoidosis of the central nervous system.

Neurosarcoidosis is a long-term chornic illness that affects the brain, spinal cord, and optic nerves.

It causes a lot of inflamation in those areas, which results in pain.

Karen went from a vibrant, 34-year-old, traveling the world to a severely sick one.

According to PEOPLE, "At times her health was so precarious she spent weeks in the hospital and she once had her last rites read when her doctors feared her respiratory system was in danger of shutting down."

There is no cure for the disease, but she is recieving treatmenet to ease the pain, a mix of steroids, morphine, a pain patch, and chemotherapy.

George has been there for her through it all- from her book releases to attending events together to just being a good friend to her.

CHRONICLING HER PAIN

Karen Duffy attends New York Premiere Of “The Social Ones” at Village East Cinema on March 3, 2020 in New York City
10
Karen Duffy attends New York Premiere Of “The Social Ones” at Village East Cinema on March 3, 2020 in New York CityCredit: Getty

Despite living with chronic pain, Karen continued to work.

In 2000, she became an author when she released her first book

The book chronicled her life in the spotlight and how it all abruptly came to an end when she received her diagnosis.

But Karen learned not to hide from life, but chose to ran towards it.

In the 2000s, she continued to work staring in smaller roles such as Fantastic Mr. Fox, Crafty, and Pepper Ann.

Karen hosted Tiny House of Horrors on TLC and appeared on Live Earth as a co-host.

Duffy told PEOPLE that being aorund her family and friends for the past 20 years has been an "important form of therapy for her."

LIFE OUT OF THE SPOTLIGHT

After the 2000s, Karen stopped acting and focused on her family and writing.

In 1997, she married John Lambros.

They had one child, Jack, together, who was born via surrogate.

George was the one who encouraged her and her husband to have a child.

It was difficult to conceive with all of the procedures she had undergone, but he helped them find a doctor to help them.

She published her second book, Backbone: Living With Chronic Pain Without Turning Into One in 2017.

It was a way she could describe her daily life with chronic pain and suffering while using humor and acceptance to cope.

George could not show up to her book launch as he was on "paternity leave," but did send a tequilla fountain.

He was featured in the book and even wrote a blurb for it.

“My friend Karen Duffy, who lives with unimaginable pain, has taught me so much; that my complaints are the most ridiculous in the world,” it read.

In her book, she told readers that she can usually only get up three days a week and the slightest touch, including wind will "sting her neck."

He is still a huge part of her life and her son's life.

He even gave them their first dog a few years ago.

Karen Duffy attends the launch of Smash + Tess X Carole Radziwill collaboration at Crosby Street Hotel on January 14, 2020 in New York City
10
Karen Duffy attends the launch of Smash + Tess X Carole Radziwill collaboration at Crosby Street Hotel on January 14, 2020 in New York CityCredit: Getty

BOOK 3 AND LIFE NOW

Karen made a surprise appearance on The Real Housewives of New York City in 2018.

That was the last time she was seen on TV.

That same year, she spoke at the

Now, Karen focuses on being a wife and mother and writer.

Her third book, was released on April 12.

The book is written in the form of letters to her 18-year-old son, Jack, with a mix of life lessons and funny stories.

Jack is a high school hockey player.

Karen recently celebrtaed her 60th birthday last year with friends and is currently co-producing two films- New Worldand The World's Greatest Beer Run Ever.

READ MORE SUN STORIES

Read More on The US Sun

Karen has used writing as a form of therapy.

She hopes her words and books inspire others and help those who live with chronic pain.

Writer Karen Duffy arrives at the American Film Institute’s 46th Life Achievement Award Gala Tribute to George Clooney on June 7, 2018 in Hollywood, California
10
Writer Karen Duffy arrives at the American Film Institute’s 46th Life Achievement Award Gala Tribute to George Clooney on June 7, 2018 in Hollywood, CaliforniaCredit: Getty
Everlast, Lisa Kennedy Montgomery, Guy Oseary and Karen Duffy at The 1993 MTV Super Bowl Show at The Rose Bowl on January 31st, 1993 in Anaheim, CA
10
Everlast, Lisa Kennedy Montgomery, Guy Oseary and Karen Duffy at The 1993 MTV Super Bowl Show at The Rose Bowl on January 31st, 1993 in Anaheim, CACredit: Getty
Karen Duffy attends The Hollywood Reporter’s Most Powerful People In Media 2018 at The Pool on April 12, 2018 in New York City
10
Karen Duffy attends The Hollywood Reporter’s Most Powerful People In Media 2018 at The Pool on April 12, 2018 in New York CityCredit: Getty

We pay for your stories!

Do you have a story for The US Sun team?

Email us at [email protected] or call 212 416 4552.

Like us on Facebook at  and follow us from our main Twitter account at 

Topics