Manchester City striker Sergio Aguero picks up calf injury for training Argentina and is doubt to face Paraguay in World Cup qualifier

SERGIO AGUERO could miss Manchester City's next Premier League clash against Everton on Saturday and is a major doubt for Argentina's World Cup qualifier versus Paraguay.

The forward picked up a calf strain in training after his country's 2-2 draw with Peru, and was replaced after 73 minutes by Ever Banega.

UPDATE: CLICK HERE TO READ THE LATEST NEWS FROM AGUERO HIMSELF ON HIS FITNESS

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Aguero, 28, is set for a scan ahead of the game in Cordoba on Tuesday - but currently has his national team coaches sweating - given they are already missing injured Lionel Messi.

The forward has scored 33 goals for his country since making his debut in 2006 and with Argentina sitting fifth in the qualifying group, they need all the help they can get.

Argentina took the lead twice in their clash with Peru on Thursday - Ramiro Funes Mori and Gonzalo Higuain but Paolo Gurrero's strike and Christian Cueva's late penalty saw both sides leave with a point.

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Pep Guardiola has already had to cope without City's star player for several games this season.

Kelechi Ihenacho had to lead the attack in the Manchester derby as City came out 2-1 winners at Old Trafford.

City face Ronald Koeman's Everton in the 3pm Saturday kick-off.

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Played or not?

A BREAKDOWN of Aguero's up-and-down season so far...

Aug 13 - Man City 2 Sunderland 1 - PLAYED 90min, scored

Aug 16 - Steaua 0 Man City 5 -  PLAYED 90min, scored hat-trick

Aug 20 - Stoke 1 Man City 4 - PLAYED 83min, scored two

Aug 24 - Man City 1 Steaua 0 - MISSED (rested)

Aug 28 - Man City 3 West Ham 1 - PLAYED, 88min

Sept 10 - Man Utd 1 Man City 2 - MISSED (suspended)

Sept 14 - Man City 4 Monchengladbach 0 - PLAYED 83min, scored hat-trick

Sept 17 - Man City 4 Bournemouth 0 - MISSED (suspended)

Sept 21 - Swansea 1 Man City 2 - MISSED (rested)

Sept 24 - Swansea 1 Man City 3 - PLAYED 90min, scored two

Sept 28 - Celtic 3 Man City 3 - PLAYED 90min

Oct 2 - - PLAYED 90min