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A BOMB has exploded in the entrance of a mosque in Kabul - leaving a number of civilians dead, a Taliban spokesman said.

The bomb targeted the sprawling Eidgah Mosque, where a memorial service was being held for the mother of Taliban spokesman Zabihullah Mujahid.

Afghan medical staff members stand at the entrance of a hospital as they wait to receive the victims of an explosion in Kabul
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Afghan medical staff members stand at the entrance of a hospital as they wait to receive the victims of an explosion in KabulCredit: AFP
Taliban fighters walk at the entrance of the Eidgah Mosque after an explosion in Kabul
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Taliban fighters walk at the entrance of the Eidgah Mosque after an explosion in KabulCredit: AP

No group has claimed responsibility but immediate suspicion is bound to fall on branch of the Islamic State known as ISIS-K.

The group were behind the deadly attack on Kabul airport in August, which killed at least 170 people.

Taliban fighters were not been harmed in the attack, Taliban spokesman Bilal Karimi told the Associated Press. 

Those killed in the attack were civilians outside the mosque gate.

He did not provide a figure for the number killed and said an investigation was ongoing.

Abdullah, a nearby shopkeeper, told AFP news agency: “I heard the sound of an explosion near the Eid Gah Mosque followed by gun firing.”

"Just ahead of the blast the Taliban had blocked the road to hold a prayer ceremony for Zabihullah Mujahid's mother in the Eid Gah Mosque."

Emergency NGO, an Italian-funded hospital in Kabul, tweeted it had received four people wounded in the blast.

A spokesman from the interior ministry, Qari Sayed Khosti, said: "Our initial information shows two civilians were killed and three wounded in the blast."

The area around the mosque was cordoned off by the Taliban, who maintained a heavy security presence.

ISIS maintains a strong presence in the eastern province of Nangarhar and considers the Taliban an enemy.

IS has claimed several attacks against the Taliban, including several killings in the provincial capital of Jalalabad.

Its rise and the attacks have raised the possibility of a wider conflict between the two extremist groups.

Attacks in Kabul have so far been rare, but in recent weeks ISIS has shown signs it is expanding its footprint beyond the east and closer toward the capital. 

On Friday, Taliban fighters raided an ISIS hideout just north of Kabul in Parwan province. The raid came after an IS roadside bomb wounded four Taliban fighters in the area.

Cars seen in a street after an explosion near the Eid Gah Mosque
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Cars seen in a street after an explosion near the Eid Gah MosqueCredit: Getty
A member of Taliban forces stands guard on a street in Kabul
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A member of Taliban forces stands guard on a street in KabulCredit: Reuters
Burka-wearing women 'forced to march' in pro-Taliban rally outside university in Kabul are escorted by armed fanatics
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