LIFE LINE

‘Wonder drug’ that helps womb cancer patients live longer and ‘see their kids grow up’ is now available on the NHS

Hundreds of women could benefit from the 'life-changing' treatment

A DRUG which could buy women with advanced or recurring womb cancer more time with their loved ones before the disease progresses is to be made available on the NHS.

The move is expected to benefit hundreds of patients each year.

Advertisement
Around 9,000 new womb cancer cases are diagnosed every year in the UKCredit: Getty
Dostarlimab is sold under the brand name Jemperli

Dostarlimab, which is sold under the brand name Jemperli, is an immunotherapy that works by attracting specific proteins on the surface of cancer cells to help the immune system attack them.

Evidence suggests the drug extends life expectancy when used alongside chemotherapy.

It will be rolled out by NHS England from Tuesday after receiving the green light from the National Institute for Health and Care Excellence (NICE), with up to 200 patients expected to be eligible each year.

Professor Peter Clark, NHS England's Cancer Drugs Fund (CDF) lead, said: "The rollout of this drug as a first-line treatment on the NHS is great news for patients living with this type of womb cancer.

Advertisement

";This new immunotherapy could offer hundreds of women the hope of precious extra time to live well before their cancer progresses."

According to NICE, there are two main types of womb cancer - endometrial cancer and uterine sarcoma - with about 9,000 new cases every year in the UK.

The most common type is endometrial cancer, with about 23 per cent of cases involving cells with a high number of mutations.

Jemperli is recommended for these subtypes where the cancer is advanced or has come back following previous treatment, NICE said.

Advertisement

Most read in Health

SHOCK TWIST
My 'cold' was a flesh-eating bug that ravaged my bum and left me close to death
WARNING SIGNS
6 surprising early signs of Alzheimer’s – from dressing scruffy to swearing
VIRAL LOAD
3 early symptoms of highly-contagious 'Kawaski bug' as GP warns 'stay at home'
NEXT THREAT
Highly-pathogenic H5N1 virus is 'poised to explode into disastrous pandemic'

Some 64 per cent of patients using Jemperli and chemotherapy in clinical trials did not see their cancer progress after 12 months of treatment.

The figure was more than twice the rate seen with chemotherapy alone (24 per cent).

Experts explain how a cancer drug could be used to treat endometriosis

However, NICE said as data was only collected over a short period of time, long-term benefits of the drug are uncertain.

It will therefore be available on the NHS through the CDF while further studies are conducted.

Advertisement

Helen Knight, director of medicines evaluation at NICE, said: "Advanced or recurrent womb cancer has a devastating effect on quality of life and there are limited treatment options available.

"We are focused on delivering what matters most and getting care to those who need it fast, so I am delighted this treatment option will be made quickly available through the CDF, enabling people with this type of cancer to enjoy more precious time with their families and loved ones."

Jemperli is administered using a 30-minute drip in hospital every three weeks alongside chemotherapy for six cycles.

Patients with cancers that have responded to the drug can have it every six weeks for up to three years.

Advertisement

One patient said the therapy has allowed her to live "without the brutal side effects" of cancer treatment.

It gives me belief that I might see my granddaughter start school

Sue WoodburnPatient

Sue Woodburn, 65, from Kirkby Lonsdale, has recurring womb cancer.

She added: "It's hard to stay positive when you're running out of options and living with cancer is taking its toll on your mental health.

"Dostarlimab has made a big difference for me. It has helped me to stay positive and hopeful that I will have a decent quality of life for a good few years yet.

Advertisement

"Dostarlimab allows me to have a treatment without the brutal side effects. It's a treatment that doesn't take over my life, that enables me to plan for the future.

"And it gives me belief that I might see my granddaughter start school.

"Now I've finished the chemo, I feel nearly back to normal.

"I've been able to travel - and have just come back from Rome.

Advertisement

"I am back biking, playing tennis and skiing - when I actually thought I would be dead by now."

Dr Chloe Barr, trustee and advocacy lead at the charity Peaches Womb Cancer Trust, welcomed the news about dostarlimab, which has been dubbed a "wonder drug".

She said: "We hope that this is just the first step towards wider availability of more effective first-line treatment options for those affected by this devastating cancer."

Advertisement

What is womb cancer?

CANCER of the womb is often called uterine or endometrial cancer.

There are around 9,000 new cases every year in the UK, making it the fourth most common cancer in women.

Symptoms include:

  • Bleeding after the menopause
  • Bleeding that is unusually heavy or persistent between periods
  • Abnormal vaginal discharge (this might be pink)
  • Anaemia
  • High platelet count
  • High blood sugar levels
  • Stomach pain
  • Swollen tummy
  • Bloating
  • Change in bowel or bladder habits
  • A new cough

Being overweight or obese is one of the biggest risks of womb cancer in the UK.

Other risk factors include age (most women diagnosed are aged 75 to 79), hormone replacement therapy (HRT), diabetes, and polycystic ovary syndrome (PCOS).

Source: Cancer Research UK

Topics
Advertisement
machibet777.com